The main purpose of this address is to touch on the current status of international grantmaking. I will do this by looking at the European perspective and by looking as a European in all modesty at the US perspective. Some of what I say may seem a bit controversial. My starting point is that there are hardly any major problems that we are confronted with that can be considered as strictly domestic. Migration and mobility, refugees, HIV/AIDS, climate instability and environment are among the issues that connect our local community with the world at large.